Document Type
Article
Keywords
Fluoroacetate, fluorocitrate, fluoroaconitate
Disciplines
Biochemistry
Abstract
The concept of lethal synthesis as suggested by Peters is reviewed in the light of the more recent work in this area. It is suggested that fluorocitrate is a "suicide" substrate for aconitase rather than a competitive inhibitor as originally suggested. The use of these substances to study glialneuronal relationships is considered
Article Number
1015
Publication Date
1991
Recommended Citation
Clarke, Donald Dudley PhD, "Fluoroacetate and fluorocitrate: mechanism of action / Donald D. Clarke" (1991). Chemistry Faculty Publications. 16.
https://research.library.fordham.edu/chem_facultypubs/16
Comments
Neurochemical research 16 no. 9:1055-1058. http://dx.doi.org/10.1007/BF00965850